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Hamartia Hamartiology Hamartoma Hamartoses Hamartomatosis Hamartomatoses

~ HAMARTIA        id+ | FLAW  FLAWED  ERROR  DEFECTIVE
                        MALFORMED  SIN |
~ HAMARTIOLOGY    id+ | THEOLOGY focused on SIN |
~ HAMARTOMA       id+ | OVERGROWTH OF MATURE CELLS
                        NORMAL TO THE SITE |
                  id+ | MALFORMED TISSUES or TUMORS |
                  id+ | FOCAL TISSUE MALFORMATION |
~ HAMARTOSES      pl of HAMARTOMA
~ HAMARTOMATOSIS  or
~ HAMARTOMATOSES  id+ | MULTIPLE HAMARTOMAS due to a
                        GENETIC MUTATION |
                  id+ | TRAGEDY |
  etym> note duality
        FLAW ERROR MALFORMATION and
        TRAGEDY
  gr HAMARTEIN = TO ERR
     HAMARTIA    FLAW  TRAGEDY  see SOPHOCLES below
  lit+ SOPHOCLES [#] in OEDIPUS REX
       illustrates HAMARTIA with
  "THE TYRANT IS A CHILD OF PRIDE
   WHO DRINKS FROM HIS GREAT SICKENING CUP
   RECKLESSNESS AND VANITY
   UNTIL FROM HIS HIGH CREST HEADLONG
   HE PLUMMETS TO THE DUST OF HOPE" and
  Alexander POPE [#] in "An Assay on Man" elaborates
  "IT IS ONLY BY KNOWING THYSELF
   THAT THOU WILT RID THYSELF
   OF THY HAMARTIA"
  med> HAMARTOMA mostly implies altered PRENATAL DEVELOPMENT of
       TISSUES in terms of "COMBINATION" "ORGANIZATION" and
  EXCESS OF GROWTH OF MATURE CELLS NORMAL TO THE SITE
  note NONETHELESS HIGH CANCER RISK MUST BE SUSPECTED
  most HAMARTOMAS MAY BE POST NATAL as per
       CARCINOGENIC CAUSES eg RADIATION WHICH DISRUPT TISSUES
  note alt definition
       HISTOLOGIC ORGANIZATION causing altered CELL GROWTH
       leading to the formation of "TUMOR" or NODULES or
  CYSTS or NEOPLASIA
  note MOST TUMORS OF THE LUNGS ARE HAMARTOMAS
  note CARDIAC HAMARTOMAS ARE OFTEN RHABDOMYOMAS ASSOCIATED WITH
       TUBEROUS SCLEROSIS
  note COWDEN SYNDROME IMPLIES MULTIPLE HAMARTOMAS
       INCLUDING OF SKIN in OVER 60% OF PATIENTS plus
  THYROID EYES etc
  note ANY INSTANCE OF MULTIPLE HAMARTOMAS SHOULD EVOKE
       SUSPICION OF A HIGH CANCER RISK SYNDROME
  sug> POLYP PAPYLOMA ADENOMA FIBROMA
       note "CYSTS" most often are HAMARTOMATOUS
  see> TERATOMA  TERATOLOGY
  med> GENETIC HAMARTOSES is a group of disorders
       included are
  NEUROFIBROMATOSES characterized by the
  development and growth of MULTIPLE hamartomas
  eg NEUROFIBROMAS LIPOMA GLIOMA
  HAMARTOMAS can undergo MALIGNANT or
  CANCEROUS or DEGENERATION thus give rise to
  SARCOMA CARCINOMA and LEUKEMIA
  cont> TRAGEDY
        

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